LONDON: Co-Chair of the Bill & Melinda Gates Foundation (BMGF) Bill Gates has said that success in the fight to wipe out polio is not guaranteed.

The philanthropist, whose foundation has poured billions into the effort, warned against complacency in tackling the deadly viral disease as he welcomed a $500 million pledge from Saudi Arabia on Sunday to fight polio over the next five years, bringing it in line with the US as one of the biggest national donors.

However, there is still a $1.2 billion dollar funding gap in the $4.8 billion budget for the Global Polio Eradication Initiative (GPEI) up to 2026, a spokesperson said. The new money from the kingdom will go some way towards closing that.

Riyadh has supported polio eradication for more than 20 years, but the significant increase in funding comes amid a “challenging” situation, said Abdullah Al Moallem, director of health at the King Salman Humanitarian Aid and Relief Centre, the kingdom’s aid arm.

Cases of polio, a viral disease that used to paralyse thousands of children every year, have declined by more than 99% since 1988 thanks to mass vaccination campaigns.

“It’s not guaranteed that we will succeed,” Gates told Reuters in an online call last week. “I feel very strongly that we can succeed, but it’s been difficult.”

The support of powerful Muslim countries such as Saudi Arabia would help, he added, particularly in addressing some lingering suspicions about vaccination.

The foundation said it would open a regional office in Riyadh to support the polio and other regional programmes.

It is allocating $4 million to humanitarian relief in Gaza, to be distributed through UNICEF, it said. The King Salman Humanitarian Aid and Relief Centre will also allocate $4 million, it said.

The first missed target for eradicating polio was in 2000, and the Bill and Melinda Gates Foundation is the largest donor trying to realise that goal.

“If we’re still here 10 years from now, people might be urging me to give up,” Gates said. “But I don’t think we will be. If things go well, we’ll be done in three years,” he said.

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